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1.
Regul Toxicol Pharmacol ; 146: 105527, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38056706

RESUMO

The Opinion of the Scientific Committee on Health, Environmental and Emerging Risks advises the European Commission on whether the uses of titanium dioxide in toys and toy materials can be considered to be safe in light of the identified exposure, and the classification of titanium dioxide as carcinogenic category 2 after inhalation. Four toy products including casting kits, chalk, powder paints and white colour pencils containing various amounts of TiO2 as colouring agent were evaluated for inhalation risks. For the oral route, childrens' lip gloss/lipstick, finger paint and white colour pencils were evaluated. When it can be demonstrated with high certainty that no ultrafine fraction is present in pigmentary TiO2 preparations used in toys and toy materials, safe use with no or negligible risk for all products considered is indicated based on the exposure estimations of this Opinion. However, if an ultrafine fraction is assumed to be present, safe use is not indicated, except for white colour pencils.


Assuntos
Corantes , Titânio , Criança , Humanos , Jogos e Brinquedos , Saúde Ambiental
2.
Regul Toxicol Pharmacol ; 80: 272-3, 2016 10.
Artigo em Inglês | MEDLINE | ID: mdl-27470440

RESUMO

The European Commission and its independent Scientific Committee on Health and Environmental Risks (SCHER) published their final Opinion on estimates of the amount of toy materials ingested by children. The SCHER was asked to review available data on the ingestion of the following three types of toy material by children, and evaluate whether the ingestion amounts which formed the basis for the migration limits of 19 elements in the Toy Safety Directive are still appropriate or whether they should be changed. In the final Opinion the SCHER considers the ingestion amounts mentioned above to be appropriate, and that these ingestion amounts should remain classified as daily amounts rather than weekly.


Assuntos
Comportamento Infantil , Exposição Ambiental/efeitos adversos , Jogos e Brinquedos , Comportamento de Sucção , Adolescente , Fatores Etários , Criança , Pré-Escolar , Qualidade de Produtos para o Consumidor , Humanos , Lactente , Recém-Nascido , Nível de Efeito Adverso não Observado , Medição de Risco , Fatores de Tempo
4.
Environ Pollut ; 138(2): 260-7, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-15955603

RESUMO

The ban on harmful substances in antifouling paints requires the development of new antifouling strategies. Alternatives should be as effective as conventional paints but of lower toxicity. In the present study two commercially available, self-polishing antifouling paints were examined in order to get information on their antifouling properties and toxicological potential. Efficacy was shown in settlement assays with the marine barnacle species Balanus amphitrite, however, efficacy was related to toxic effects observed on target and non-target organisms. Toxicity of the paint extracts was concentration-dependent and differed according to the paint and the species investigated. Toxicity could at least partially be attributed to zinc leached from the paints. Effects of a water-soluble paint were more pronounced in larvae of B. amphitrite, Artemia salina and in the green algae Dunaliella tertiolecta. Embryos of the freshwater species Danio rerio and Vibrio fisheri were more affected by a paint based on organic solvents.


Assuntos
Pintura/toxicidade , Controle de Pragas , Praguicidas/toxicidade , Poluentes Químicos da Água/toxicidade , Aliivibrio fischeri , Animais , Eucariotos , Larva , Dose Letal Mediana , Água do Mar , Thoracica , Testes de Toxicidade Aguda , Peixe-Zebra , Zinco/toxicidade
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